Agenda

Sunday,  March 31

 
Reception (6 pm)  
Plenary lecture (7 pm)  
Emilio Carbone  L-type calcium channels in pacemaking, secretion and autism viewed through mouse models
Opening dinner (8 pm)  
   
   

Monday, April 1

 
Channelopathies (8:30 am):  
Terry Snutch P/Q-type channels: splicing, synapses and spreading depolarization 
Tuck Wah Soong Calcium-dependent facilitation of Cav2.1 channel and ataxia
Philippe Lory New Cav3 channelopathies
Ivy Dick Calcium channel deficits underlying cardiac arrhythmias: from mechanisms to therapy
Jeff Noebels Isolating minimal brain circuitry of mutant calcium channel epilepsies
Ivana Souza Short talk: R-type calcium channel mutations in pediatric epilepsy patients
   
Neurophysiology:  
Anjali Rajadhyaksha Impact of Cav1.2 channel deficiency in the prefrontal cortex on social behavior 
Heesup Shin Thalamic low threshold bursts in control of fear memory
Roger Thompson Pannexin-1 channels as critical mediators of non-ionotropic NMDAR dependent LTD
Arn van den Maagdenberg Cav2.1 channels in disease: from mutations to models and shared mechanisms
Jing Zhai Short talk: Deletion of IQ-domain RNA editing in Cav1.3 channel enhances spatial learning and memory
   
   

Tuesday, April 2

 
Calcium channels and pain (8:30 am):  
Gerald Zamponi Calcium dysregulation during chronic pain
David Adams Analgesic α-conotoxins targeting neuronal calcium channels directly and via GPCR activation
Atsufumi Kawabata Distinct effects of T-type Ca2+ channel blockers and genetic deletion of Cav3.2 on somatic and visceral hypersensitivity
Jin Tao Methylation of miRNA contributes to trigeminal neuralgia by regulating Cav3.2 expression
Mike Hildebrand Contributions of T-type channels towards spinal pain processing
Norbert Weiss Homocysteinemia in pain processing – a role for T-type channels
Emmanuel Bourinet Spinal Cav3.2 T-type channels modulates sensory and affective related symptoms of neuropathic pain
   
Synaptic physiology:  
Dick Tsien Calcium channels and unconventional synaptic signaling
Luyang Wang Functional modules of voltage-gated calcium channels in gating transmitter release
William Catterall Calcium channel regulation, synaptic plasticity, and spatial learning
   
   

Wednesday, April 3

 
Subunits/protein complexes (8:30 am):  
Annette Dolphin Studies on the mechanism of action of auxiliary alpha2delta subunits
Gerald Obermair/Stefanie Geisler Presynaptic α2δ subunits of voltage-gated calcium channels regulate synaptic connectivity
David Luo In vitro characterization of aberrant sensory neuron synapse formation involving voltage gated calcium channel α2δ-1 subunit proteins
Manua Ben-Johny Allosteric modulation of Cav channels by stac proteins 
Filip van Petegem Structural insights into the binding and regulation of L-type calcium channels by calmodulin and STAC proteins
Ray Turner FMRP as a constituent member of the Cav3-Kv4 complex
Gary Stephens Modulation of T-type calcium channels by the CACHD1 protein
Marta Campiglio Short talk: STAC3 – the missing link in skeletal muscle excitation-contraction coupling
Giriraj Sahu Short talk: Cav1.3 forms a tri-protein complex to drive the slow AHP in hippocampal pyramidal cells
Hadhi Asmara Short talk: A dynamic T-type-Calmodulin interaction activates aCaMKII and CREB
   
Cardiovascular physiology:  
Livia Hool The role of the L-type calcium channel and extracellular matrix stiffness in the regulation of cardiac metabolic activity
Matteo Mangoni Functional role of L-type Cav1.3 channels in adrenergic regulation of cardiac pacemaker activity
   
   

Thursday, April 4

 
Calcium signaling (8:30 am):  
Brian MacVicar The impact on brain function of frequency dependent coupling between neuronal activity and mitochondrial calcium dynamics
Stefan Herlitze Optogenetic control and visualization of changes in intracellular calcium levels. 
Mark Shapiro Synergistic interplay between various calcium-permeable ion channels direct nervous function in brain and peripheral neurons
Peter Stys Axonal Ca dynamics and the axo-myelinic synapse
Maria Gandini Short talk: Quantitative imaging of a fluorescent Cav3.2 T-type channel biosensor
   
Distribution/expression:  
Elizabeth (Liz) Tunbridge The diversity of Cav1.2 isoforms in human brain
Akos Kulik Differential subcellular distribution and regulatory role of Cav1 and Cav2 channels in hippocampal neurons
Miguel Martin-Caraballo Post-transcriptional regulation of Cav3.2 T-type calcium channel subunit by interleukin-6 in prostate cancer cells: role of miR-32
Mario Giocobassi Using Ca Imaging to functionally differentiate between neuronal subclasses.
Baldomero Olivera Defining voltage gated Ca channel expression in different DRG neuronal subclasses
Olena Fedorenko Short talk: Expression of voltage-dependent calcium channels in adipocytes
Nneoma Akaniro-Ejim Short talk: Characterisation and functional regulation of lL-type calcium channels in white fat adipocytes
   
Reception (6 pm)  
Conference dinner (7 pm)  
   
   

Friday, April 5

 
Pharmacology/gating (8:30 am):  
Steffen Hering On the link between activation and inactivation in Cav1.2
Richard Lewis ω-conotoxin interactions at N-type Cavs
Henry Colecraft Towards more precise Cav channel inhibitors
Arnaud Monteil Setting up a functional assay to search for modulators of neuronal sodium leak channels (NALCN)
Slobodan Todorovic Different roles of T-type calcium channel isoforms in neurosteroid anesthesia
Toru Ogawa Short talk: Drug discovery research for novel Cav3.2 channel antagonists
   
Neurodevelopment/neurodegeneration:  
James Surmeier Cav1 calcium channels link regenerative activity to bioenergetic control in neurons
Brigit Liss Voltage gated calcium channels in Parkinsons disease
Stephen Ferguson Sex-specific differences in mGluR5 signaling in AD mouse models
Yong Li DUSP6 SUMOylation protects cells from oxidative damage via direct regulation of Drp1 dephosphorylation
Sean Cregan Short talk: Regulation of ER-mitochondrial calcium dynamics and neuronal cell death by Bcl-family proteins
Nadine Ortner Short talk: Cav1.3 L-type calcium channels in neurodevelopmental disorders