Sunday, March 31
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| Reception (6 pm) |
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| Plenary lecture (7 pm) |
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| Emilio Carbone |
L-type calcium channels in pacemaking, secretion and autism viewed through mouse models |
| Opening dinner (8 pm) |
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Monday, April 1
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| Channelopathies (8:30 am): |
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| Terry Snutch |
P/Q-type channels: splicing, synapses and spreading depolarization |
| Tuck Wah Soong |
Calcium-dependent facilitation of Cav2.1 channel and ataxia |
| Philippe Lory |
New Cav3 channelopathies |
| Ivy Dick |
Calcium channel deficits underlying cardiac arrhythmias: from mechanisms to therapy |
| Jeff Noebels |
Isolating minimal brain circuitry of mutant calcium channel epilepsies |
| Ivana Souza |
Short talk: R-type calcium channel mutations in pediatric epilepsy patients |
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| Neurophysiology: |
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| Anjali Rajadhyaksha |
Impact of Cav1.2 channel deficiency in the prefrontal cortex on social behavior |
| Heesup Shin |
Thalamic low threshold bursts in control of fear memory |
| Roger Thompson |
Pannexin-1 channels as critical mediators of non-ionotropic NMDAR dependent LTD |
| Arn van den Maagdenberg |
Cav2.1 channels in disease: from mutations to models and shared mechanisms |
| Jing Zhai |
Short talk: Deletion of IQ-domain RNA editing in Cav1.3 channel enhances spatial learning and memory |
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Tuesday, April 2
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| Calcium channels and pain (8:30 am): |
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| Gerald Zamponi |
Calcium dysregulation during chronic pain |
| David Adams |
Analgesic α-conotoxins targeting neuronal calcium channels directly and via GPCR activation |
| Atsufumi Kawabata |
Distinct effects of T-type Ca2+ channel blockers and genetic deletion of Cav3.2 on somatic and visceral hypersensitivity |
| Jin Tao |
Methylation of miRNA contributes to trigeminal neuralgia by regulating Cav3.2 expression |
| Mike Hildebrand |
Contributions of T-type channels towards spinal pain processing |
| Norbert Weiss |
Homocysteinemia in pain processing – a role for T-type channels |
| Emmanuel Bourinet |
Spinal Cav3.2 T-type channels modulates sensory and affective related symptoms of neuropathic pain |
| Maria Gandini |
Short talk: Splice variant dependent opiod receptor modulation of N-type calcium channels |
| Synaptic physiology: |
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| Dick Tsien |
Calcium channels and unconventional synaptic signaling |
| Luyang Wang |
Functional modules of voltage-gated calcium channels in gating transmitter release |
| William Catterall |
Calcium channel regulation, synaptic plasticity, and spatial learning |
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Wednesday, April 3
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| Subunits/protein complexes (8:30 am): |
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| Annette Dolphin |
Studies on the mechanism of action of auxiliary alpha2delta subunits |
| Gerald Obermair/Stefanie Geisler |
Presynaptic α2δ subunits of voltage-gated calcium channels regulate synaptic connectivity |
| David Luo |
In vitro characterization of aberrant sensory neuron synapse formation involving voltage gated calcium channel α2δ-1 subunit proteins |
| Manua Ben-Johny |
Allosteric modulation of Cav channels by stac proteins |
| Filip van Petegem |
Structural insights into the binding and regulation of L-type calcium channels by calmodulin and STAC proteins |
| Ray Turner |
FMRP as a constituent member of the Cav3-Kv4 complex |
| Gary Stephens |
Modulation of T-type calcium channels by the CACHD1 protein |
| Marta Campiglio |
Short talk: STAC3 – the missing link in skeletal muscle excitation-contraction coupling |
| Giriraj Sahu |
Short talk: Cav1.3 forms a tri-protein complex to drive the slow AHP in hippocampal pyramidal cells |
| Hadhi Asmara |
Short talk: A dynamic T-type-Calmodulin interaction activates aCaMKII and CREB |
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| Cardiovascular physiology: |
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| Livia Hool |
The role of the L-type calcium channel and extracellular matrix stiffness in the regulation of cardiac metabolic activity |
| Matteo Mangoni |
Functional role of L-type Cav1.3 channels in adrenergic regulation of cardiac pacemaker activity |
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Thursday, April 4
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| Calcium signaling (8:30 am): |
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| Stefan Herlitze |
Optogenetic control and visualization of changes in intracellular calcium levels. |
| Mark Shapiro |
Synergistic interplay between various calcium-permeable ion channels direct nervous function in brain and peripheral neurons |
| Peter Stys |
Axonal Ca dynamics and the axo-myelinic synapse |
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| Distribution/expression: |
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| Elizabeth (Liz) Tunbridge |
The diversity of Cav1.2 isoforms in human brain |
| Akos Kulik |
Differential subcellular distribution and regulatory role of Cav1 and Cav2 channels in hippocampal neurons |
| Miguel Martin-Caraballo |
Post-transcriptional regulation of Cav3.2 T-type calcium channel subunit by interleukin-6 in prostate cancer cells: role of miR-32 |
| Mario Giocobassi |
Using Ca Imaging to functionally differentiate between neuronal subclasses. |
| Baldomero Olivera |
Defining voltage gated Ca channel expression in different DRG neuronal subclasses |
| Olena Fedorenko |
Short talk: Expression of voltage-dependent calcium channels in adipocytes |
| Nneoma Akaniro-Ejim |
Short talk: Characterisation and functional regulation of lL-type calcium channels in white fat adipocytes |
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| Reception (6 pm) |
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| Conference dinner (7 pm) |
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Friday, April 5
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| Pharmacology/gating (8:30 am): |
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| Steffen Hering |
On the link between activation and inactivation in Cav1.2 |
| Richard Lewis |
ω-conotoxin interactions at N-type Cavs |
| Henry Colecraft |
Towards more precise Cav channel inhibitors |
| Arnaud Monteil |
Setting up a functional assay to search for modulators of neuronal sodium leak channels (NALCN) |
| Slobodan Todorovic |
Different roles of T-type calcium channel isoforms in neurosteroid anesthesia |
| Toru Ogawa |
Short talk: Drug discovery research for novel Cav3.2 channel antagonists |
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| Neurodevelopment/neurodegeneration: |
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| James Surmeier |
Cav1 calcium channels link regenerative activity to bioenergetic control in neurons |
| Brigit Liss |
Voltage gated calcium channels in Parkinsons disease |
| Stephen Ferguson |
Sex-specific differences in mGluR5 signaling in AD mouse models |
| Yong Li |
DUSP6 SUMOylation protects cells from oxidative damage via direct regulation of Drp1 dephosphorylation |
| Sean Cregan |
Short talk: Regulation of ER-mitochondrial calcium dynamics and neuronal cell death by Bcl-family proteins |
| Nadine Ortner |
Short talk: Cav1.3 L-type calcium channels in neurodevelopmental disorders |